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VP/Senior Director Translational Biology - London

Translational Research · London, London, City of
Department Translational Research
Employment Type Full-Time
Minimum Experience Executive


Gyroscope: Vision for Life

Gyroscope Therapeutics is building something special – a company to preserve people’s sight and fight the devastating impact of blindness around the world. And if we are successful, our gene therapies and surgical devices will offer people the chance to see what they otherwise would have missed.

To be successful we need the right people. People who have passion for helping patients. People who can work as one toward a common goal, have fun and together bring forward the best ideas. People who celebrate success and embrace failure as an opportunity to learn and grow. If you are one of these people, we would love to meet you.

Position Summary

Direct all Translational Research related product development activities through development of Board approved strategies aligned with high level project plans. Deliver Pre-Clinical and Clinical stage biological assays to support the portfolio progression alongside having oversight of research plans and directing research strategy to identify new targets and elucidate complex Disease Biology.


Role Responsibilities

  • Lead the Early Product Development including in-licensing strategies, plan and advocate for Governance and Board meetings and manage budget
  • Manage and develop a Translational Research Team capable of delivering to corporate milestones. Identify, develop and transfer (as required) new assay systems and analytical techniques to address Translational/Research questions and improve exiting techniques
  • Set-up and management of GCLP lab to support Clinical Development
  • Management and development of the Complement Biology team, elucidate disease biology and identify new targets
  • Ensure all required documentation and reports are completed and approved in a timely manner, ensuring validity and reliability of data
  • Effective cross-functional interaction with other departments, especially Clinical Development and Clinical Operations
  • Collaborate with Clinical Development to lead the cross-functional Translational team
  • Seek and leverage external network/KOLs community
  • Deliver projects and translational Research activities to budget and on time


Experience Required

  • Proven track record of R&D project leadership; leading teams to investigate scientific hypotheses leading to understanding of targets and discovery of NME
  • Experience of translating assets from pre-clinical to clinical stage
  • Experience of leading teams and developing team members
  • Experience of representing Research at Board/Governance meetings to gain approval for budget and Product Development Strategies
  • Experience of establishing early development through management of external CROs and Academic Collaborations
  • Ability to work to priorities and deliver to time
  • Ability to communicate complex information clearly
  • Ability to assess resource requirements and deploy them effectively
  • Ability to live the Gyroscope culture and encourage behaviour within team
  • London Based position


Education and Skills Required

  • PhD or equivalent experience with >10 years of experience in pharmaceutical/biopharmaceutical/gene therapy product development
  • Ophthalmology experience is desirable

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  • Location
    London, London, City of
  • Department
    Translational Research
  • Employment Type
  • Minimum Experience